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Multicenter study on diagnosis of central sleep apnea complicated with heart failure by diaphragm electromyogram and efficacy of bi-level positive airway pressure ventilation

Multicenter study on diagnosis of central sleep apnea complicated with heart failure by diaphragm electromyogram and efficacy of bi-level positive airway pressure ventilation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12003881
Enrollment
Unknown
Registered
2012-07-02
Start date
2014-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

central sleep apnea complicated with chronic heart failure

Interventions

BiPAP group:BiPAP

Sponsors

Jiangsu Geriatric Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients from 18-75yeardiagnosis of stable chronic heart failure (NYHA I-III, LVEF450pg/ml); 2. Patients have accepted optimal medical therapy for at least one month; 3. Apnea hypopnea index of central sleep apnea tested by diaphragm electromyogram more than 15/h.

Exclusion criteria

Exclusion criteria: CHF was caused by: 1. Valvular disease, congenital heart disease, pericardial disease, cardiac arrhythmia or other non-cardiogenic factors; 2. Those who is likely to undergo coronary artery bypass graft surgery or cardiac resynchronization therapy during the following 12 weeks; 3. Patients with left ventricular outflow obstruction, myocarditis, an aneurysm, uncontrolled severe arrhythmia, cardiogenic shock, unstable angina or acute myocardial infarction; had severe primary hepatic, renal, or hematologic disease or had a severe mental disease or other uncontrolled systemic disease.

Design outcomes

Primary

MeasureTime frame
AHI;NT-proBNP;

Secondary

MeasureTime frame
LVEF;6 min walk test;life quality score;

Countries

China

Contacts

Public ContactLu Gan

Jiangsu Geriatric Hospital

lugan0121@163.com+86 13851782662

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026