Clinical Trial Protocol for the Behavioral and Imaging Study of the Compound Congrong Yizhi Capsule Intervenes in Mild Cognitive Impairment

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12003073

Enrollment

Unknown

Registered

2012-11-05

Start date

2012-11-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment

Interventions

Group B (Control Group):Placebo

Group A(Drug Group):Compound Congrong Yizhi Capsule

Eligibility

Sex/Gender

All

Age

50 Years to 80 Years

Inclusion criteria

Inclusion criteria: (The following 5 items are required to comply with): (1) Cognitive decline: chief complaint or an insider reports that subject has cognitive impairment problem, and objective examination provides evidence of cognitive impairment; or(and) the objective examination confirmed cognitive function of subject declined over the past; (2) Daily basic living ability must be normal, permits minor damage in the ability of using complex tools; (3) Without dementia; (4) Aged 50 to 80 years; (5) The patient or their legal guardians signed the informed consent.

Exclusion criteria

Exclusion criteria: (Subjects would be exclusive when complied any of the item following) (1) Transient ischemic attack (TIA); (2) Cerebral hemorrhage or subarachnoid hemorrhage; (3) Check confirmed that the stroke was caused by brain tumors,brain trauma and blood diseases; (4) Cerebral embolism caused by atrial fibrillation with rheumatic heart disease, coronary hear t disease or any other heart diseases; (5) Bone and joint diseases and some other serious diseases which were associated with liver, kidney, hematopoietic system and endocrine system etc.; (6) Bone and joint diseases and some other serious diseases which were associated with liver, kidney, hematopoietic system and endocrine system etc.; (7) Mental disorders or severe dementia; (8) Patients can not be performed with MRI which has accepted pacemaker surgery, coronary intervention surgery or coronary artery bypass surgery; (9) Patients can not be performed with MRI which has a magnetic implant inside.

Design outcomes

Primary

Measure	Time frame
Mini-Mental State Examination (MMSE);	—

Secondary

Measure	Time frame
Auditory Verbal Learning Test;Montreal cognitive assessment(MoCA);Symbol Digit Modalities Test (SDMT);Boston Naming Test;Digit Span;Clock Drawing Test;Stroop test;Trail Making Test;Activities of Daily Living(ADL);	—

Countries

China

Contacts

Public ContactZHANG Zhan-Jun

zhang_rzs@bnu.edu.cn+86 010 58802005

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026