Evaluation of the effectiveness of Parecoxib Sodium in comparison to placebo in open thoracic surgery under general anesthesia with epidural analgesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002997

Enrollment

Unknown

Registered

2012-11-06

Start date

2013-02-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

open thoracic surgery

Interventions

test group:parecoxib sodium 40mg IV preoperatively

control:0.9%NS

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) age 18-60 years;2) ASA classification grade ? - ?;3) patients scheduled for open thoracic surgery;4) with normal pre-operative routine tests results, including CBC, liver and kidney function (ALT and AST, BUN, and Cr = upper limit of normal), and coagulation functions;5) patient compliance: with a clear consciousness, and be able to cope with the follow-up assessment.

Exclusion criteria

Exclusion criteria: 1) patients with the following underlying diseases: history of active ulcer or bleeding in the upper digestive tract; history of ischemic heart disease or cerebrovascular disease; renal dysfunction; spinal diseases; 2) infection in the puncture site; 3) bacteremia; 4) preoperative bleeding and coagulation disorders, or perioperative use of anticoagulant drugs; 5) patient refused to sign the informed consent.

Design outcomes

Primary

Measure	Time frame
pain score;	—

Secondary

Measure	Time frame
dosage of local anaesthetia;	—

Contacts

Public ContactNuo-er SANG

sangnuoerpumch@yahoo.com.cn+86 010-69154278

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026