hepatic failure occurred in patients with chronic hepatitis B of severe degree
Conditions
Interventions
group 1 of intergrated traditional Chinese medicin:genearl internal medicine treatment and traditional Chinese medicine treatment such as cooling blood and activating blood and so on
group 2 of intergrated traditional Chinese medicin:genearl internal medicine treatment and traditional Chinese medicine treatment by using the therapeutic principle "tonifying the kidney to regulate s
Sponsors
Hubei Province Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patient should conform to hepatic failure diagnosis standard that defined in the diagnosis and treatment guidline of hepatic failure in 2006; 2. Patient had chronic hepatitis B or compensatory liver cirrhosis of hepatitis B; 3. Patient should be a volunteer who had signed the information consent firm; 4. Patient should be aged between 18 and 65 years old.
Exclusion criteria
Exclusion criteria: 1. Patient had acute hepatic failure; 2. Patient had chronic hepatic failure occured with other disease except chronic hepatitis B; 3. Patient was pregnancy or lactation woman; 4. Patient had primary hepatocellular carcinoma; 5. Patient was complicated with other severe systematic disease and mental disease, as well as drug users who hard to withdraw; 6. Patient had positive reaction of anti-HIV, or was complited with cytomegalovirus, EB virus and other hepatotropic virus infection; 7. Patient had attended other clinical studies in last three months; 8. Patient did not cooperate with the study; 9. Patient was poor compliance, and unable to guarentee to complete the protocol; 10. Patient was compicated with severe cerebral edema, severe infectious, type I liver-kidney symdrom, and massive hemorrhage of gastrointestinal tract.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| case fatality rate;incidence of complication; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effectiveness evaluation;Improvment rate of Traditional Chinese Medicine clinical symtoms;Traditional Chinese medicine clinical syndrome evaluation;MELD score;The improvement of the quality of life situation; | — |
Countries
China
Contacts
Public ContactLi Han-min
Outcome results
None listed