Type 2 Diabetes
Conditions
Interventions
A:umbilical cord mesenchymal stem cell transplantation
B:anti-diabetic drugs or insulin injection
Sponsors
General Hospital of Chinese People's Armed Police Forces
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria included the following: the patients were between the ages of 18 and 70 years, male or female; they had poor glycemic control with recent anti-diabetic therapies, including drugs and/or insulin injection for at least three months; they had a negative result in testing for the glutamic acid decarboxylase antibody; they had not been pregnant or nursing; they had a fasting blood glucose (FBG) level >=7.0 mmol/L and HbA1c>=7%; and they had a good organic sufficiency, including heart, liver, kidney and lung, to receive interventional therapy.
Exclusion criteria
Exclusion criteria: acute or chronic infections; any malignancies; hematological diseases or coagulopathy; known immunosuppressive disease (e.g., acquired immunodeficiency); acute or chronic pancreatitis; and a history of thoracic or abdominal aorta diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycated hemoglobin;C-peptide;Glycemia;Beta-cell function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin requirement and oral hypoglycemic drugs;Immunologic cells tests;Inflammatory cytokines (IL-1 beta, IL-6, IL-10 and TNF); | — |
Countries
China
Contacts
Public ContactYihua an
Outcome results
None listed