Coronary heart disease acute exacerbation of chronic heart failure
Conditions
Interventions
Experimental:Basal therapy+Shenfu injection 50ml mix with 5% glucose injection 100ml intravenous infusion onece a day
control:Basal therapy+5% glucose injection 100ml intravenous infusion onece a day
Sponsors
The First Affiliated HospitaI of Tianjin University of TraditionaI Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Meet the Coronary heart disease acute exacerbation of chronic heart failure diagnostic standard; 2. 40~79 years of age; 3. The NYHA grade for heart failure should be III~IV; 4. Signed the inform consent.
Exclusion criteria
Exclusion criteria: 1. Acute coronary syndrome, onset of acute myocardial infarction within past 6 months, revascularization whithin past six months, or plan to revasculariation in the near future, cardioc shock, fatal arrhythmia, Cardiomyopathy, Constrictive pericarditis, Pulmonary embolism, etc.; 2. Severe liver, renel disfunction (ALT higher than the normal value three folders, and Cr>=3mg/dL; 3. Complicated with endocrine system, blood system severe original diseases; 4. Woman plan to pregnance in followed three months, or lactating women; 5. Mental disease patient; 6. Allergic constitution, or known allergy for the test drug; 7. Attended other clinical studies in past three months; 8. To be judged that the patient unable to alive less than three months; 9. To be judged the patient cannot complete the study or do not complain the rule of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NYHA;TCM symptom scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| echocardiogram examination;NA;Lee's Heart failure score;6-minute walk test;Cardiovascular events, Re-hospitalization rate; | — |
Countries
China
Contacts
Public ContactMao Jingyuan
Outcome results
None listed