The study of the correlation between nosociomial infections and gut microflora in critically ill patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002854

Enrollment

Unknown

Registered

2012-09-16

Start date

2013-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nosociomial infections

Interventions

probiotic group:orally administered probiotics

control group:placebo

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: patients admitted to internal intensive care unit of Huadong Hospital, including patients who are under mechanical ventilation, jaundice, after chemotherapy or radiotherapy, intestinal obstructed, bedridden after stroke and so on.

Exclusion criteria

Exclusion criteria: -age less than 18 years old, pregency; -severe gastrointestinal disease: maligant tumor,short bowel disease,hepatic cirrhosis (Child C); -severe immunosuppression: AIDS,neutrophil count less than 500/mm3; -combine with other infection passages such as gastrointestinal fistula, renal fistula, indwelling catheter; -take in probiotics during past 4 weeks; -dying patients.

Design outcomes

Primary

Measure	Time frame
incidence of nosociomial infections;mortality;gut microflora count;	—

Secondary

Measure	Time frame
sIg A;length of stay;IL-6;endotoxin;CRP;pathogen of nosociomial infection;CRP;	—

Countries

China

Contacts

Public ContactJieming Qu

jmqu64@yahoo.com.cn18901661180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026