Efficacy of a Supplemented Low Protein Diet for Proteinuric Patients With Early-stage Primary Glomerular Disease

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002821

Enrollment

Unknown

Registered

2012-12-28

Start date

2010-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Glomerular Disease

Interventions

test group:keto-supplemented low protein diet

control group:normal protein diet

Eligibility

Sex/Gender

All

Age

18 Years to 76 Years

Inclusion criteria

Inclusion criteria: 1. Proven by renal biopsy as primary glomerular disease, urine protein excretion no less than 2000mg after a four-week treatment of standardized glucocorticoid and an additional immunosuppressant needed; 2. Adult patients aged more than 18 years; 3. Estimated glomerular filtration rate >=60ml/min/1.73m2; 4. All patients received therapy of telmisartan 80mg/d; 5. An informed consent was obtained from every subject.

Exclusion criteria

Exclusion criteria: 1. Patients with urine protein excretion less than 2000mg four weeks after glucocorticoid therapy; 2. Secondary glomerular diseases; 3. Chronic wasting disease, or acute inflammatory; 4. Stress, or life-threatening state; 5. BMI >=28 kg/m2 or <=14 kg/m2; 6. pregnancy or lactation.

Design outcomes

Primary

Measure	Time frame
24-hour urine protein excretion;Serum creatinine;eGFR;Serum prealbumin;lipids profile;	—

Secondary

Measure	Time frame
Serum albumin;	—

Countries

China

Contacts

Public ContactHongli Lin

linhongli@vip.163.com+86 13332268576

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026