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The flurbiprofen axetil used in postoperative continuous wound algesia in elderly patients with thoracic surgery: a randomized, double-blind, placebo-controlled study

The clinical Research of flurbiprofen axetil used in continuous wound algesia in elderly patients with thoracic surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002816
Enrollment
Unknown
Registered
2012-12-19
Start date
2012-12-14
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer and lung placeholder

Interventions

Sponsors

Department of Anesthesiology, First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Patients with elective thoracic surgery undergoing general anesthesia only; 2) Age> 65 years; 3) Cardiac function II-III, ASA II-III; 4) patients agreed to participate in the study and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1) a history of angina or congestive heart failure, myocardial infarction, coronary revascularization, coronary artery bypass, stroke or transient ischemic attack, uncontrolled hypertension or diabetes, liver disease, kidney disease, bleeding disordersother disorders; 2) NSAIDs, opioids, local anesthetics, or sulfa drugs, allergy, or the presence of significant clinical or laboratory abnormalities history thus contraindicated the fluoride than Los disputes ester or opioids's patients; 3) The recent history of abuse of alcohol and pain medication, or potent opioids and antidepressant drug treatment history of patients; 4) If NSAIDs was token, at least a 72-hour washout period is needed, and provide weak opioid tramadol drug as an alternative; 5) incision of the chest and abdomen or the chest and abdomen, neck incision postoperative patients; perioperative hemodynamic volatility caused by bleeding, arrhythmia; the postoperative convalescence severe hypercapnia and significantly waking delay; 6) patients unable to cooperate, or can not understand and implement VAS scores of patients.

Design outcomes

Primary

MeasureTime frame
Postoperative VAS scores;morphine consumption until 48 h after surger;

Secondary

MeasureTime frame
Blood platelet;Renal function;

Countries

China

Contacts

Public ContactQi Zhao
zhaoqingmz2010@163.com+86 13856085989

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026