Esophageal cancer and lung placeholder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients with elective thoracic surgery undergoing general anesthesia only; 2) Age> 65 years; 3) Cardiac function II-III, ASA II-III; 4) patients agreed to participate in the study and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1) a history of angina or congestive heart failure, myocardial infarction, coronary revascularization, coronary artery bypass, stroke or transient ischemic attack, uncontrolled hypertension or diabetes, liver disease, kidney disease, bleeding disordersother disorders; 2) NSAIDs, opioids, local anesthetics, or sulfa drugs, allergy, or the presence of significant clinical or laboratory abnormalities history thus contraindicated the fluoride than Los disputes ester or opioids's patients; 3) The recent history of abuse of alcohol and pain medication, or potent opioids and antidepressant drug treatment history of patients; 4) If NSAIDs was token, at least a 72-hour washout period is needed, and provide weak opioid tramadol drug as an alternative; 5) incision of the chest and abdomen or the chest and abdomen, neck incision postoperative patients; perioperative hemodynamic volatility caused by bleeding, arrhythmia; the postoperative convalescence severe hypercapnia and significantly waking delay; 6) patients unable to cooperate, or can not understand and implement VAS scores of patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative VAS scores;morphine consumption until 48 h after surger; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood platelet;Renal function; | — |
Countries
China