chronic hepatitis C
Conditions
Interventions
YI QI JIE DU group:1 bag YI QI JIE DU bid po.
SHU GAN JIAN PI group:1 bag SHU GAN JIAN PI bid po.
BU SHEN ROU GAN group:1 bag BU SHEN ROU GAN bid po.
control group 1:1 bag placebo bid po.
control group 2:1 bag placebo bid po.
control group 3:1 bag placebo bid po.
Sponsors
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medcine
Eligibility
Sex/Gender
All
Age
12 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Voluntary participation in the trial, and signed informed consent; 2. Aged 12 to 75 years; 3. Patients who meet the diagnostic criteria of CHC, and positive HCVRNA 4. Failed with standard of care and dont willing to accept SOC again; 5. Have the contraindication of SOC; 6. Cannot tolerate the side effects of SOC; 7. Not willing to or havre no economic capacity to accept SOC; 8. Separated into different groups with syndrome differentiation.
Exclusion criteria
Exclusion criteria: 1. Co-infection with HIV, HBV, HDV and other hepadnaviruses are excluded; 2. With chronic severe hepatitis, cirrhosis or liver cancer; 3. With severe primary cardiac,lung, kidney, blood, metabolism, gastrointestinal or affect the survival of serious diseases, or Mental disorders; 4. Pregnancy, breast-feeding women; 5. ALT>=5*ULN and/or TBIL>=3*ULN; 6. can not give fully informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HBV DNA virus load; | — |
Secondary
| Measure | Time frame |
|---|---|
| Liver function;ultrasonic B examination;Chronic liver disease instrument;clinical symptom;quality of life; | — |
Countries
China
Contacts
Public ContactJianjie Chen
Outcome results
None listed