liver cancer
Conditions
Interventions
IORT group:Radiotherapy during surgery operation
Sponsors
Cancer Institute & Hospital. Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 75 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria can be categorized as follows: (1) centrally located HCC with no preoperative radiotherapy; (2) resectable lesion appraised by our surgery panel, with possibility of completely removing tumors and retaining a sufficient residual liver to maintain liver function; (3) aged between 17 and 75 years; (4) compensated cirrhosis or no cirrhosis; (5) Child–Pugh liver function class A; (6) Eastern Cooperative Oncology Group Performance Status (ECOG PS) of 0 or 1; (7) Patients who had received previous trans-arterial chemoembolization were eligible for enrolment in the study. The therapy must have been stopped at least 4 weeks before study entry; (8) Patients volunteered for this study and provided written informed consent.
Exclusion criteria
Exclusion criteria: (1) presence of distant metastasis; (2) resection margin > 1cm; (3) palliative resection with tumor residual; (4) non-HCC confirmed by pathology; (5) severe allergic history or hypersensitive constitution.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| recurrent-free survival; | — |
Countries
China
Contacts
Public ContactWu Jianxiong
Outcome results
None listed