Comparative Study of Human Aqueous Humor Levels of Gatifloxacin 0.3% Eye Gel, Gatifloxacin 0.3% and Levofloxacin 0.5% Ophthalmic Solution after Topical Dosing

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002693

Enrollment

Unknown

Registered

2012-11-14

Start date

2010-08-09

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endoophthalmitis after cataract surgery

Interventions

gatifloxacin 0.3% eye gel:One drop of gatifloxacin 0.3% eye gel was administration

gatifloxacin 0.3% ophthalmic solution:One drop of gatifloxacin 0.3% ophthalmic solution

levofloxacin 0.5% ophthalmic solution:One drop of levofloxacin 0.5% ophthalmic solution

Eligibility

Sex/Gender

All

Age

44 Years to 91 Years

Inclusion criteria

Inclusion criteria: age-related cataract patients undergoing phacoemulsification with posterior chamber intraocular lens implantation.

Exclusion criteria

Exclusion criteria: 1. patients who were suffering from any ocular diseases, such as high myopiauveitisocular trauma; 2. diabetes mellitus and any other metabolic disease; 3. those who were allergic to the drug used in the experiment; 4. those who were using drugs may influence the experimental results; 5. those who were accepting other therapies may influence the experimental results.

Design outcomes

Primary

Measure	Time frame
aqueous humor level of each drug;	—

Countries

China

Contacts

Public ContactYao Ke

xlren@zju.edu.cn+86 0571-87783897

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026