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To explore the mechanism of action of liver controlling dispersion and regulating emotions from the viewpoint of the liver to treat mild and moderate depression

To explore the mechanism of action of liver controlling dispersion and regulating emotions from the viewpoint of the liver to treat mild and moderate depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002684
Enrollment
Unknown
Registered
2012-07-05
Start date
2012-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild and moderate depression

Interventions

Shuyu granule group:Shuyu granule
Shuyu granule plus minus group:Modified Shuyu granule
Control:fluoxetine

Sponsors

Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. The subjects in line with ICD-10 depressive episode diagnostic criteria, mild or moderate; 2. Aged 18 to 65 years; 3. The subjects with clear consciousness and independent judgment; 4. The subjects can understand the purpose of this study and voluntarily coordinate.

Exclusion criteria

Exclusion criteria: Subjects suffering from depression due to organic disease or psychoactive substances and non-addictive substances.

Design outcomes

Primary

MeasureTime frame
5-HT;NE;ANG ?;Glucocorticoid;Melatonin;Gastrin;Homocysteine;Progesterone;TNF-alpha;NO;—

Secondary

MeasureTime frame
E2;PRL;LH;FSH;TSH;—

Countries

China

Contacts

Public ContactQiao Mingqi
qmingqi@163.com+86 13553168096

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026