Efficacy and Safety of probiotics for the prevention of child antibiotic-associated diarrhea

Effective of Saccharomyces boulardii for preventing child antibiotic-associated diarrhea: a multicenter randomized controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002654

Enrollment

Unknown

Registered

2012-11-05

Start date

2012-11-12

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Antibiotic associated diarrhea

Interventions

Test group:Saccharomyces boulardii

Control:Basical treatment and blank control

Eligibility

Sex/Gender

All

Age

No minimum to 3 Years

Inclusion criteria

Inclusion criteria: 1. Age 1 month-3 years; 2. Non-gastrointestinal infections in hospitalized children While require antibiotic treatment; 3. Treatment of the primary diarrhea on admission, stool normal; 4. The use of antibiotics: Not more than three days before admission, More than faive days after admission.

Exclusion criteria

Exclusion criteria: 1. Children with diarrhea when admission to hospital; 2. Children with severe immunodeficiency; 3. Chileren with CVC; 4. Inpatient treatment during the application of antifungal drugs in children; 5. Children of drug allergy.

Design outcomes

Primary

Measure	Time frame
incidence;	—

Secondary

Measure	Time frame
Stool frequency;Stool properties;Duration of diarrhea;The degree of dehydration;Laboratory test;	—

Countries

China

Contacts

Public ContactChaomin Wan

haj6909@yahoo.com.cn+86 13982105587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026