Effect of Different Excipients of Propofol on Plasma Lipid and Hepatic Function in Periampullary Carcinoma Patients Undergoing Whipple Procedure with general anesthesia

Clinical study of the infusion of differnt concentration MCT/LCT propofol's effect on Plasma Lipid and Hepatic Function in Patients Undergoing Whipple Procedure with general anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002627

Enrollment

Unknown

Registered

2012-10-18

Start date

2012-11-15

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Changes of Plasma Lipid and Hepatic Function

Interventions

Study group:2%MCT/LCT propofol

Control group:1%MCT/LCT propofol

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Periampullary carcinoma patients will conduct Whipple procedure; 2. 18-75 years, male or female; 3. ASA I-III; 4. BMI 18.5-30; 5. Have signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients allergic to components of propofol MCT/LCT or propofol LCT, soya or peanut; (2) Pregnant or lactating women; (3) Patients with alcohol or drug abuse; (4) Patients with mental disorders or epilepsy; (5) Patients with with renal dysfunction, SCr >1.2mg/dl; (6) Cardiac dysfunction, NYHA III-IV; (7) Patients with a tumor unsectable; (8) Patients have used propofol within 1 month; (9) Patients have participated in other clinical trials within 3 months.

Design outcomes

Primary

Measure	Time frame
Plasma triglyceride (TG) concentration;	—

Secondary

Measure	Time frame
liver function;Plasma lipid parameters;kidney function(SCr BUN);Routine blood test;serum potassium;blood glucose;	—

Countries

China

Contacts

Public ContactYue Yun

yueyun@hotmail.com+86 10 85231463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026