Severe burn injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patient takes part in the test voluntarily and signs the informed consent statement; 2. TBSA>=30%; 3. Admitted within 48 hours after injury; 4. age between 18 to 65 years old, no matter of gender; 5. No obvious signs of shock; 6. No serious diseases of heart, liver, lung, kidney or blood system; 7. No obvious systemic infection.
Exclusion criteria
Exclusion criteria: 1. patient who does not will to join the test; 2. patient younger than 18 or older than 65 years old; 3. patient with tumor, AIDS, diabetes or autoimmune diseases; 4. patient with specific infection such as tuberculosis, legionella and others; 5. Pregnant or breastfeeding woman; 6. patient with systemic failure; 7. patient with coagulation dysfunction; 8. patient who suffered cardiac infraction or cerebrovascular accident within past 6 months; 9. Patient who has poor adaptivity and cannot complete treatment schedual of the trial. Patient who has a serious disease of the heart, liver or kidney, or had a blood producing disorder, and inclination to bleed or bleeding disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| passing through shock phase;stress indexes in blood;complications and final outcome; | — |
Secondary
| Measure | Time frame |
|---|---|
| stress indexes in effluent;indexes in urine; | — |
Countries
China