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308nm excimer laser + Betamethason Copound Injection vs. tacrolimus ointment + Betamethason Copound Injection for the treatment of advanced face and neck vitiligo: efficacy and safety of the multi-center, randomized, open, parallel, self-controlled clinical trials

308nm excimer laser + Betamethason Copound Injection vs. tacrolimus ointment + Betamethason Copound Injection for the treatment of advanced face and neck vitiligo: efficacy and safety of the multi-center, randomized, open, parallel, self-controlled clinical trials

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002594
Enrollment
Unknown
Registered
2014-09-21
Start date
2012-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo

Interventions

test group:308nm excimer laser + compound betamethasone injection
control group:Tacrolimus ointment + compound times betamethasone injection

Sponsors

The First Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) age 10-70 years old, inpatient or outpatient, male or female; (2) meet the diagnostic criteria of clinically diagnosed with primary advanced (advanced standards, see Annex 2) patients with vitiligo of the face and neck; (3) subjects volunteered to participate, be required to sign an informed consent form; (4) leukoplakia spread in the neck of the double-side, with at least one lesions greater than 1cm in diameter.

Exclusion criteria

Exclusion criteria: (1) pregnant and lactating women; (2) serious heart, liver, renal insufficiency; (3) pre-cancerous skin lesions; (4), systemic lupus erythematosus (SLE), dermatomyositis ultraviolet treatment contraindications; (5) with immunosuppressive therapy; Nearly 2 months (6) received corticosteroids, calcineurin inhibitors, NB-UVB excimer laser treatment, any treatment received nearly January, at the same time to participate in clinical trials; (7) can not adhere to treatment; (8) tacrolimus sensitive; (9) secondary vitiligo (secondary to discoid lupus erythematosus, chronic eczema, vitiligo).

Design outcomes

Primary

MeasureTime frame
Lesions change;

Countries

China

Contacts

Public ContactXing-hua Gao
gaobarry@hotmail.com+86 13940152467

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026