Effects of preventively subsedative dose of dexmedetomidine on the quality of postoperative sleep of elderly critically patients: prospective random controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12002567

Enrollment

Unknown

Registered

2012-10-10

Start date

2012-11-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

dexmedetomidine:continuous infusion of dexmedetomidine (0.1ug/kg/h for 15 hours)

control:continuous infusion of saline (0.1ug/kg/h for 15 hours)

Eligibility

Sex/Gender

All

Age

65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Elderly (>65 years) patients; 2. Undergoing elective non-cardiac surgery with general anesthesia; 3. Admitted to SICU after operation.

Exclusion criteria

Exclusion criteria: 1. Unwilling to participate in the study; 2. History of psychiatric disorders,epilipsia,parkinson's disease or myasthenia gravis; 3. Preoperative coma, dementia,communication deficiency; 4. craniocerebral trauma and neurosurgery; 5. Preoperative LVEFII degree atrioventricular block; 6. Preoperative severe dysfunction of liver (Child-Pugh class C); 7. Severe renal dysfunction(preoperative renal replacement therapy); 8. Preoperative ASA grade IV or presumptively survive for less than 24h; 9. other unsuitable cases.

Design outcomes

Primary

Measure	Time frame
the structure and ciecle of sleep;subjective sleep quality;	—

Secondary

Measure	Time frame
the incidence of postoperative delirium;stay time of postoperative ICU;the occurrence of postoperative complications and 30-day mortality;	—

Countries

China

Contacts

Public ContactWang Dong-xin

wangdongxin@hotmail.com+86 13910731903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026