postoperative analesia and postoperative recovery of bowel function
Conditions
Interventions
control:controventional postoperative care regimen
G:sugarless gum
GN:sugarless gum
Sponsors
West China Second University Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: All subjects aged 18~50 yr, scheduled to undergo advanced elective laparoscopic gynecological procedures; All patients were American Society of Anesthesiologists (ASA) physical status I or II.
Exclusion criteria
Exclusion criteria: Exclusion criteria were current or recent smoking history within the last 6 mo, a history of uncontrolled hypertension, ischemic heart disease, arrhythmias, stroke, respiratory disease, peptic ulcer disease, peritoneal carcinomatosis, inflammatory bowel disease, previous gastric or esophageal surgery (due to vagus nerve injury), or gut motility influencing agents (for example, tricyclic antidepressants), pregnancy, chronic pain, drug or alcohol abuse, or use of chronic pain medications, the use of spinal or epidural anesthesia during the operation, and known allergy to and of the study medications. Patients were excluded if there was a history of psychiatric disorder. Patients receiving regular opioids or drugs with known analgesic properties in the 24 h before surgery were also excluded. Furthermore, patients with disturbance of acetylcholine metabolism in any way, such as neurological disease, medication (SSRI), or depression were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue score; | — |
Secondary
| Measure | Time frame |
|---|---|
| time to first flatus;time to first defecation;the incidence of nause during the first 12 hours after surgery;the incidence of vomiting during the first 12 hours after surgery;the blood pressure during 12 hours after surgery;the heart rate during 12 hours after surgery;the requirement of analgesics during the first 6 hours/12 hours/24 hours after surgery;the requirement of antiemetic during the first 6 hours/12 hours/24 hours after surgery;the amounts of pro-inflammatory factors(TNF-a/IL-1b/IL-6) in patients plasma;the length of hospital stay; | — |
Countries
China
Contacts
Public ContactHua Feng Li
Outcome results
None listed