Cardiac andgastric fundus diease (including flat polyp, high grade intraepithelial neoplasia andintramucosal carcinoma etc.)
Conditions
Interventions
Hemocoagulase group:2U hemocoagulase adding into 100ml saline for injection. Multi-point submucosal injection by the lateral edge of lesions, each point with about 2ml. Repeating injection is permitte
Control group:2ml of 1:10000 diluted epinephrine adding into 100ml saline for injection. Multi-point submucosal injection by the lateral edge of lesions, each point with about 2ml. Repeating injection
Sponsors
First Affiliated Hospital of Suzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years old, sex is not limited; 2. With cardiac andgastric fundus dieases (including flat polyp, high grade intraepithelial neoplasia andintramucosal carcinoma etc.), andis going to be treated by ESD; 3. Able andwilling to provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Severe cardiovascular, renal, liver disease, such as severe cardiopulmonary or renal insufficiency; 3. Disturbance of blood coagulation; 4. Contraindications of hemocoagulase treatment; 5. Mental disorder or disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemorrhage volume in operation;Intraoperative hemorrhage grading;Ratio of Immediate and delayed hemorrhag; | — |
Countries
China
Contacts
Public ContactRui Li
Outcome results
None listed