diabetes
Conditions
Interventions
metformin treatment group:metformiin
non-metformin treatment group:non-metformin treatment
Sponsors
First Affiliated Hospital of Chongqing Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. type 2 diabetes is diagnosed through 75g OGTT based on the diagnostic criteria of World Health Organization (WHO) in 1999; 2. No biguanides have been taken last 3 months; 3. type 2 diabetes patients should only taken glimepiride as anti-diabetes medicine, and HbA1c should below 7.0%.
Exclusion criteria
Exclusion criteria: 1. Women who were currently pregnant and breastfeeding; 2. allergic with biguanides; 3. people who not willing to accept dynamic blood glucose monitoring; 4. subjects with hypertension, coronary heart disease and other chronic diseases history; 5. patients with diabetic nephropathy, diabetic peripheral neuropathy, diabetic foot, diabetic retinopathy and histories of other diabetes chronic complications; 6. patients with diabetic acute complications, such as diabetic ketosis. paitents with abonormal hepar and renal functions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| height;weight;blood pressure;fasting plasma glucose;2h postchallenge plasma glucose;fasting insulin;blood lipids;MAGE;MODD;HbA1; | — |
Secondary
| Measure | Time frame |
|---|---|
| ICAM-1;VCAM-; | — |
Countries
China
Contacts
Public ContactJang Long
Outcome results
None listed