severe acute pancreatitis
Conditions
Interventions
Standard medical treatment group:Standard medical treatment
Sponsors
Department of transfusion, Daping Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with severe acute pancreatitis (APACHEII>=8; Ranson>=3;or CT Balthazar: D or E degree); 2. Both male and female between 18-70 years of ages; 3. The duration of the disease <=5 days (begin with the onset of abdominal pain), without surgical indications at admission; 4. Patients voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Allergies or patients has an allergy to drugs used in this study; 2. Active bleeding or bleeding tendency obviously, DIC, shock and hemodynamic instability; 3. Pregnant or breast-feeding women; 4. Patients with mental disorder or disease; 5. Patients accepted any blood products within 3 month before the study; 6. Patients already received blood purification (such as PE or hemofiltration) treatment before the study; 7. Participate in other clinical trials within 3 month before the study; 8. Other cases which researchers believe that can not enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| APACHE II score;cure rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| APACHE II score;length of stay;index of inflammation;time of start eating;cost of hospitalization;major complications;local complications;mortality; | — |
Countries
China
Contacts
Public ContactAiqing wen
Outcome results
None listed