primary hypertension
Conditions
Interventions
P1:All subjects reveive acupuncture at Taichong for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
P2:All subjects reveive acupuncture at Taixi for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
P3:All subjects reveive acupuncture at Taichong and Taixi acupoints for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
P4:All subjects reveive acupuncture at non-acupoint for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
P5:All subjects reveive acupuncture at Taichong and non-acupoint for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
N1:All subjects reveive acupuncture at Taixi for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
N2:All subjects reveive acupuncture at Taixi for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
N3:All subjects reveive acupuncture at Taichong and Taixi acupoints for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
N4:All subjects reveive acupuncture at non-acupoint for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
N5:All subjects reveive acupuncture at Taichong and non-acupoint for 30 min, proceed blood pressure measurement and cerebral function imaging by fcMRI
Sponsors
Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The healthy volunteers: 1. students without acupuncture experience between the ages of 21 to 28 years old; half male and half female; 2. regular diet, no propensity with alcoholic, tobacco, coffee and tea, normal sleep(go to bed before 12 clock at night) and moderate size(BMI is between 20-25 for male and 19-24 for famale); no mental or nervous system disease history; 3. Volunteers should be informed and sign the informed consent. The primary hypertension: 1. patients at preliminary diagnosis between the ages of 18 to 55 years old for male and 18 to 65 for female, right handedness, male and female both are allowed; 2. patients in the state of I or II phase according to the diagnosis and risk stratification standard of "hypertension guide" amended and issued in 2003 of the World Health Organization (WHO)/International Hypertension League (ISH); 3. The syndrome differentiation of TCM is deficiency of Yin leading to hyper activity of Yang (Typing of syndrome differentiation refers to the standard of "Guidelines for the Clinical Research of Chinese Medicine New Drugs "(Trial) established by State Chinese Medicine Administration); 4. Volunteers should be informed and sign the informed consent.
Exclusion criteria
Exclusion criteria: Healthy volunteers should be excluded: 1. with all kinds of pain (including dysmenorrhea) and insomnia that may affect the treatment effect in the near future (1 month); 2. history of any metallic implant in the body,like heart stent or metal dentures; 3. dermatosis or skin damage near the acupoint where acupuncture would be applied; 4. with thrombocytopenia, hemophilia, blood coagulation dysfunction disease or the history of faintng during acupuncture treatment; 5. no response or excessive sensitive reaction in the acupuncture response pretest which is hold 1 month before the test; received other acupuncture treatment 1 month before the test; 6. Over reactive to noise, low temperature environment and history of claustrophobia. Hypertension volunteers should be excluded: 1. secondary hypertension, hypertension of pregnancy; 2. With serious disease of other organs, and other diseases like diabetes, hemophilia, coagulant function obstacle patients; 3. Mental patients, pregnancy and nursing mothers; 4. Dermatosis or skin damage near the acupoint where acupuncture would be applied; 5. Received other treatments for hypertension during the experimental observation period; 6. with all kinds of pain (including dysmenorrhea) and insomnia that may affect the treatment effect in the near future (1 month); 7. history of faintng during acupuncture treatment; 8. Over reactive to noise, low temperature environment and history of claustrophobia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cerebral functional activity;blood pressure; | — |
Contacts
Public ContactHuang Yong
Outcome results
None listed