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Closed-loop feedback computer-controlled phenylephrine for maintenance of blood pressure during spinal anaesthesia for caesarean section: randomized comparison of automated bolus versus infusion

Closed-loop feedback computer-controlled phenylephrine for maintenance of blood pressure during spinal anaesthesia for caesarean section: randomized comparison of automated bolus versus infusion

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002418
Enrollment
Unknown
Registered
2012-08-13
Start date
2012-07-25
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

maintenance of blood pressure during spinal anaesthesia for caesarean section

Interventions

Two groups :Computer-controlled delivery system 30 min approximately versus Computer-controlled administration of phenylephrine by automated bolus or infusion

Sponsors

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status 1 or 2 normotensive non-labouring parturients with term singleton pregnancies who are scheduled for elective Caesarean section and who have been judged suitable and have agreed to have for spinal anaesthesia according to usual clinical criteria.

Exclusion criteria

Exclusion criteria: Known fetal abnormality, preexisting or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease, thrombocytopaenia, coagulopathy, or any medical contraindication to spinal anaesthesia, age 100 kg, height 180 cm, inability or refusal to give informed consent.

Design outcomes

Primary

MeasureTime frame
Median absolute performance error for systolic blood pressure in the first 10 min after spinal injection;Maternal heart rate and cardiac output - from spinal injection until delivery. Umbilical cord blood gases and neonatal Apgar scores – after delivery.;

Countries

China

Contacts

Public ContactProf Warwick D. Ngan Kee
warwick@cuhk.edu.hk+852 26322735

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026