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Levofloxacin (Cravit) versus Moxifloxacin-concentration of epithelial lining fluid in patients with idiopathic pulmonary fibrosis (IPF)

Levofloxacin (Cravit) versus Moxifloxacin-concentration of epithelial lining fluid in patients with idiopathic pulmonary fibrosis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002372
Enrollment
Unknown
Registered
2012-07-15
Start date
2011-02-23
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic pulmonary fibrosis

Interventions

Cravit IPF Group:Cravit 500 mg per time
Cravit Normal Pulmonary Function Group:Cravit 500 mg per time
Moxifloxacin IPF Group:Moxifloxacin 400mg per time
Moxifloxacin Normal PulmonaryFunction Group:Moxifloxacin 400mg per time

Sponsors

Respiratory Department, Peking Union Medical College Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age: from 18 to 70 years; 2. Agenda: Male or Female; 3. Inpatient or outpatient; 4. Negative result in the pregnancy test; 5. Diagnosis as IPF and need to conduct the bronchoscope test.

Exclusion criteria

Exclusion criteria: 1. Serious heart, liver, and renal disease; 2. hormone or immunosuppressive agent treatment patients; 3. Serious gastrointestinal disease patients; 4. has used levofloxacin or other quinolone drugs seven days before enrollment; 5. Investigator thinks that there are any situations which will add the patient's risk or influence the study results. And so on.

Design outcomes

Primary

MeasureTime frame
Drug Concentration of BALF and blood after 3.5 hours treatment;

Countries

China

Contacts

Public ContactZuo-jun Xu
xuzjpumch@yahoo.com.cn+86 010-69156114

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026