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Effects of 7.2% hypertonic saline-hydroxyethyl starch (HS-HES) in the intraoperative fluid management of the neurosurgical patients.

Effects of 7.2% hypertonic saline-hydroxyethyl starch(HS-HES) in the patients undergoing the neurosurgical procedures in terms of clinical, hemodynamic and laboratory variables.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002357
Enrollment
Unknown
Registered
2012-07-20
Start date
2011-07-20
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neurological anesthesia

Interventions

HS-HES:250ml of HS-HES
HES:1000ml of HES

Sponsors

Beijing Sanbo Brain Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
19 Years to 60 Years

Inclusion criteria

Inclusion criteria: To be aged between 18 to 80 years, elective neurosurgical procedures with general anesthesia or intracanal anesthesia, ASA I-II, without the history of organic dysfunction or coagulation dysfunction, without allergy to the starch.

Exclusion criteria

Exclusion criteria: Signs of significantly increased intracranial pressure (ICP), history of cardiac, pulmonary and renal dysfunctions, fluid or electrolyte disturbances, preoperative coagulation disorders and preoperative treatment with diuretics and/or osmotic agents.

Design outcomes

Primary

MeasureTime frame
intraoperative total fluid input;fluid balance;dural tension score;—

Secondary

MeasureTime frame
hemodynamic variable;—

Countries

China

Contacts

Public ContactBaoguo Wang
wbgttyy@sina.com+86 10 62856766

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 24, 2026