hand-foot and mouth disease (HFMD)
Conditions
Interventions
Treatment:Jinlian Qingre Effervescent Tablets
Control:Placebo
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: 1. Subject who has a clinical diagnosis of Hand, Foot and Mouth Disease (HFMD); 2. Subject who has a Evil Committed Feipi Card syndrome differentiation of TCM; 3. Subjects' highest axillary temperature was between 37.3 and 38.6 degree C within 24 hours before onset 4. the course of disease <=24 hours; 5. subjects 3 years ~6 years of age (< 7 years); 6. interventions(such as antibiotics, antiviral class)or other treatments have not been used after the onset 7. The subjects' legal guardian must be aware of this trail,and voluntarily participate in the study and signed Informed Consent Form.
Exclusion criteria
Exclusion criteria: 1. A suspected hand, foot and mouth disease in patients with severe (with a nervous system involvement, convulsions, coma, or herniation, severe and critical performance) and chicken pox, herpes angina, atypical measles, children acute rash of herpes zoster, and rubella, papulesurticaria patients; subjects who have stomach Deficiency, or easy to diarrhea; 2. hyperglycemia; 3. ALT and AST >= 1.5 times ULN; 4. subjects with severe malnutrition, severe primary disease of rickets patients and combined heart, brain, lung, liver, kidney and hematopoietic and other systems, and the mentally ill; 5. Allergic constitution (more than two classes of material allergy), or composition of the test drug allergy 6. Any condition that in the opinion of the investigator, may interfere with the evaluation of study objectives 7. Participate in other clinical trials in the latest week.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time of body temperature going back to normal; | — |
Secondary
| Measure | Time frame |
|---|---|
| time of the herpes /rashes(including canker sore);time of the herpes /rashes(including canker sore);curative effect of TCM syndrome;deterioration ratio;throat swab Virus-negative transfer ratio; | — |
Countries
China
Contacts
Public ContactSiyuan Hu
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Outcome results
None listed