critical ill patients(APACHE ?scores>12points)
Conditions
Interventions
A:feeding Ensure
B:feeding JEVITY
Sponsors
The First Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age > 18 years old; 2. The APACHE II score > 12 points; 3. Have enteral nutrition indications and is expected to take enteral nutrition >=5 days; 4. Have signed the information consent form.
Exclusion criteria
Exclusion criteria: 1. severe hemodynamic instability; 2. Have the enteral nutrition contraindications (active gastrointestinal hemorrhage, ileus,abdominal compartment syndrome (ACS), acute pancreatitis, acute stage of inflammatory bowel disease, etc); 3 .White blood cells < 10^9/L; 4. Be allergic to any ingredient of the products; 5. Have participated in another researchIn within 2 months before the start of the study; 6. Whom the researchers thought not suitable for the study; 7. Whom be reluctant to sign the information consent form or follow the research plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the rate of gastrointestinal adverse reaction;Laboratory examinations(blood routine, liver and kidney function,blood lipid level, CRP);fat granule at each high magnification field of vision; | — |
Secondary
| Measure | Time frame |
|---|---|
| D-lactic acid level in blood;intestinal fatty acid binding protein level in the blood;Clostridium difficile toxins in the stool;Coccus: bacillus proportion in the stool; | — |
Countries
China
Contacts
Public ContactBin Ouyang
Outcome results
None listed