Schizophrenia
Conditions
Interventions
1:paliperidone extended-release
Sponsors
First Affiliated Hospital, College of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Male or female patient aged 18-45 years were included in the study if they fulfilled the diagnostic criteria for schizophrenia of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition; 2. Body mass index (BMI) between 18-30 kg/m2; 3. Not ever received any antipsychotic treatment or had stopped previous antipsychotic for at least 3 months.
Exclusion criteria
Exclusion criteria: 1. Previous treatment with paliperidone or olanzapine, clozapine, or antidepressant within 1 month; 2. Currently treated with insulin or oral antidiabetic agents, patients with a known diagnosis of diabetes or hyperlipidemia; 3. Current substance abuse; 4. Medical condition that may affect glucose/lipid metabolism; 5. Pregnant female patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight;subcutaneous fat;waist circumference;hip circumference;fasting glucose;fasting insulin;glycohemoglobin A1;cholesterol;triglycerides;high density level cholesterol;low density level cholesterol;prolactin;body mass index;homeostasis insulin resistance;homeostasis beta-cell function; | — |
Countries
China
Contacts
Public ContactYi Xu
Outcome results
None listed