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60d head-down bed rest study

The effects of simulated microgravity induced by long term head-down bed rest on human physiological functions and countermeasure research

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002254
Enrollment
Unknown
Registered
2012-06-10
Start date
2007-08-16
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiological effects induced by microgravity

Interventions

Control:head-down bedrest for 60 days
Oral chinese medicine:oral Chinese medicine during the 60d- bedrest
whole body vibration with resistive exercise:resistive exercise with whole body vibration during 60d-bedrest

Sponsors

China Astronaut Research and Training Center
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Chinese citizen, male, aged 25-40, height 162-175cm, BMI 18.5-24.9; 2. Good health, not be addicted to smoking and alcohol, currently not being treated by medical theraphy and no drug dependence; 3. No history of mental, psychological, genetic and infectious diseases; 4. Agree to participate in this study and informed agreement signed.

Exclusion criteria

Exclusion criteria: 1. Having organic disease(especially skeleton and cardiovascular diseases); 2. Taking drugs which have effects on the bone metabolism in half of a year; 3. Having serious allergic history; 4. Having metal implant in the body; 5. color blindness and color amblyopia; 6. Not sign the informed agreement.

Design outcomes

Primary

MeasureTime frame
Echography;Skin microcirculation function;autonomic nerve function;vascular characteristics;orthostatic tolerance;hypergravity tolerance;exercise cardiopulmonary function;MRI;beat by beat finger blood pressure;Heart rate variability;bone mineral density;isokinetic muscle force;pQCT;blood biochemical parameters;psychological assessment;

Countries

China

Contacts

Public ContactLi Yinghui
yinghuidd@vip.sina.com+86 010 66362021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026