Nonfunctioning pituitary tumors
Conditions
Interventions
sevoflurane deep anesthesia:Tidal volume induction with 8% sevofluran and 8 L/min O2, Remifentanil 1ug/kg.min for one min followed by 0.3ug/kg.min, Rocuronium 0.6mg/kg. Tracheal intubation was conduct
sevoflurane light anesthesia:Tidal volume induction with 8% sevofluran and 8 L/min O2, Remifentanil 1ug/kg.min for one min followed by 0.3ug/kg.min, Rocuronium 0.6mg/kg. Tracheal intubation was conduc
Sponsors
Department of Anesthesiology, Tongji Hospital, Tongji Medical College of Huazhong University of Science & Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patient accepted transsphenoidal surgery for non-functional pituitary adenoma; Age 18-65 years old; no gender limitation; ASA1-2; weight 40-80 kg; operation time of 1-2 hours
Exclusion criteria
Exclusion criteria: Liver and kidney dysfunction; lactating women; preoperative confusion unable to cooperate; obvious respiratory cardiovascular disease; functional pituitary tumor back to ICU with endotracheal tube posoperatively;participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The lag time of extubation(the time interval between NTI was 80 and extubation);The extubation time(the time interval between withdrawing sevoflurane and extubation); | — |
Secondary
| Measure | Time frame |
|---|---|
| Emergence agitation (Emergence agitation was assessed by Restlessness score (RS));Postoperative sedation (It was assessed by Ramsay Sedation Score (RSS));VAS; | — |
Countries
China
Contacts
Public ContactFang Luo
Outcome results
None listed