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Changes in Hemodynamic and Respiratory Parameters in Sedation for Gastrointestinal Endoscopy: A Comparison between Target-Controlled Propofol Infusion Alone and Intermittent Bolus of a Sedative-Analgesic Cocktail Regimen

Changes in Hemodynamic and Respiratory Parameters in Sedation for Gastrointestinal Endoscopy: A Comparison between Target-Controlled Propofol Infusion Alone and Intermittent Bolus of a Sedative-Analgesic Cocktail Regimen

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002200
Enrollment
Unknown
Registered
2012-05-25
Start date
2009-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal disease

Interventions

None listed

Sponsors

None
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
58 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients who were referred from outpatient clinic for diagnostic/therapeutic upper endoscopy or colonoscopy and asked for sedation during the examination were enrolled into the present study. After obtaining institutional board approval and patient’s written consent form, consecutive 205 adult patients (79 patients undergoing upper endoscopy and 126 patients undergoing colonoscopy) were incorporated into the study. All patients belonged to American Society of Anesthesiologists (ASA) physical status class I or II.

Exclusion criteria

Exclusion criteria: Patients of ASA class III or IV were excluded from the study. Other exclusion criteria were patient’s refusal to join the study, possibility of pregnancy, history of habitual narcotic use or allergy to any drug used in the study (propofol, midazolam or alfentanil).

Design outcomes

Primary

MeasureTime frame
blood pressure;heart rate;oximetry;

Contacts

Public ContactChan Wei-Hung
andrchan@ms34.hinet.net0972651607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026