Free-Flowing Tuberculous Effusions
Conditions
Interventions
one lumen central venous catheterization placed
urokinase instillation
Double lumen tube group:standard anti-TB medications
double lumen central venous catheterization placed
urokinase instillation Intervention
control group:standard anti-TB medications in addition to therapeutic thoracentesis
Single lumen tube group:standard anti-TB medications
Sponsors
Institute of Surgery Research, Daping Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. non encapsulated tuberculous pleurisy; 2. agree to participate in clinical trials; 3. age from12 to 80 years old.
Exclusion criteria
Exclusion criteria: Absolute contraindication: 1. Any trauma,surgery, or major hemorrhage within 48 hrs; 2. Bronchopleural fistula; 3. History of allergic reaction to the drug. Relative contraindication or precaution: 1. Coagulation abnormality(or therapeutic anticoagulation); 2. Invasive thoracic or abdominalsurgery in the previous 2 wks; 3. History of cranial hemorrhage; 4. Surgery or trauma to the head inthe previous 2 wks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of residual pleural thickening;The total effusion volumes remove; | — |
Countries
China
Contacts
Public ContactCao Guoqiang
Outcome results
None listed