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Proprietary Chinese Medicine ER-XIE-TING for Acute Diarrhea in Children: A Randomized, Multicenter, Active-Controlled Trial

A Multicenter, Randomized, Active-Controlled Study to Evaluate the Efficacy and Safety of Proprietary Chinese Medicine ER-XIE-TING in Children with Acute Diarrhea

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002152
Enrollment
Unknown
Registered
2012-05-07
Start date
2011-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-infectious enteritis, rotavirus enteritis

Interventions

Observation group:Rehydration therapy + proprietary Chinese medicine ER-XIE-TING
Control group:Rehydration therapy + Smectite ? Powder

Sponsors

Children's Hospital , Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 3 Years

Inclusion criteria

Inclusion criteria: 1. Parents (or Guardian) of children signed the informed consent voluntarily and will to accept corresponding intervention and to receive follow-up on time; 2. Age of all patients were between 1 and 36 months; 3. Diagnosis is acute diarrhea, and duration of symptoms was less than 72 hours. All patients had watery or loose stools and no bloody purulent stools.

Exclusion criteria

Exclusion criteria: 1. Patients with frequent vomiting or can't eat anything; 2. Stool routine showed more than 5 WBC or 3 RBC per HP; 3. Patients with severe dehydration and severe disturbance of electrolytes; 4. Patients with structural abnormity of digestive system or ever received operations of GUT; 5. With serious disease of heart, liver, or immunodeficiency disease; 6. With severe malnutrition; 7. Bacterial enteritis or treated with antibiotics; 8. Patients who are in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Outcome Assessment;

Secondary

MeasureTime frame
Duration of symptoms and sign;

Countries

China

Contacts

Public ContactJie Chen
hzcjie@zju.edu.cn+86 13858032920

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026