nephrotic syndrome
Conditions
Interventions
treatment group:Given furosemide treatment
control group:Not given furosemide treatment
Sponsors
the Affiliated Hospital of Guangdong Medical College
Eligibility
Sex/Gender
All
Age
10 Years to 70 Years
Inclusion criteria
Inclusion criteria: The patients chosen diagnosed as nephrotic syndrome patients with minimal changes, membranous nephropathy, focal segmental glomerulosclerosis (FSGS) or severe edema.
Exclusion criteria
Exclusion criteria: 1. nephrotic syndrome in severe pathological type (such as crescentric glomerulonephritis); 2. The patients had obvious chronic renal tubule-interstitium injury which were proved by pathology, or the patients may have chronic renal tubule-interstitium injury due to recurrence and long-term irregular treatment; 3. The patients who use suspicious nephrotoxic drugs (including traditional Chinese medicine) and the disease time of nephrotic syndrome is more than 2 months, or have complex or unclear medical history; 4. The patients who use any diuretics within 2 weeks; 5. The patients diagnosed as obvious hypovolemia in clinic; 6. The patient with moderate hypertension and cardiac function ? or higher; 7. The patients with financial difficulties or bad compliance, then probably their length of stay would less than one week; 8. The patients with urinary tract infection (the number of WBC in urine is greater than 3/HP).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NGAL;IL-18;KIM-1;TGF-beta; | — |
Countries
China
Contacts
Public ContactLiu Huafeng
Outcome results
None listed