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Prospective randomized trial to evaluate the efficacy of topical Xylocaine gel versus Alcaine eye drops in the pain control in LASIK Surgery

Prospective randomized trial to evaluate the efficacy of topical Xylocaine gel versus Alcaine eye drops in the pain control in LASIK Surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002139
Enrollment
Unknown
Registered
2012-05-01
Start date
2007-06-04
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myopia, corneal sensation

Interventions

Two groups:Proparacaine and lidocaine (gel) vs Proparacaine and hydroxypropyl-methylcellulose (gel) for 2 mins

Sponsors

Nil
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Any persons greater than 18 years of age, requiring LASIK for refractive errors correction under topical anesthesia who agrees to participate in the study and in whom pain scores can be reliably assessed; 2. Cooperative enough to receive LASIK under topical anesthesia by gel / eye drops 3.Willing to participate and give a consent after full explanation of the aims, risks and benefits of the study.

Exclusion criteria

Exclusion criteria: 1. Patients with other ocular or systemic conditions, which are painful or require the regular use of analgesics; 2. Patients with medical, psychological and social conditions predisposing to a different perception of pain; 3. Patients who do not want to receive the gel during the LASIK procedure; 4. Patients not cooperative or patient with conditions that prevent them to cooperate to undergo the LASIK procedure under topical anesthesia by gel / eye drops; 5. Anisometropia > 1.5D.

Design outcomes

Primary

MeasureTime frame
Pain scores during application of anaesthesia, during the procedure (application of lid speculum, flap creation and laser application).;

Secondary

MeasureTime frame
Overall acceptance of the procedure Complication related to pain or discomfort.;

Countries

China

Contacts

Public ContactProf. Dennis SC Lam
dennislam_cu_res@cuhk.edu.hk+852 27623157

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026