Pregnancy
Conditions
Interventions
Two groups:Norepinephrine versus Phenylephrine 30 min approximately
Sponsors
Prince of Wales Hospital, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists Physical Status 1 or 2 normotensive non-labouring parturients with term singleton pregnancies who are scheduled for elective Caesarean section and who have been judged suitable and have agreed to have for spinal anaesthesia according to usual clinical criteria.
Exclusion criteria
Exclusion criteria: Known fetal abnormality, preexisting or pregnancy-induced hypertension, known cardiovascular or cerebrovascular disease, thrombocytopaenia, coagulopathy, or any medical contraindication to spinal anaesthesia, weight 100 kg, height 180 cm, inability or refusal to give informed consent, age < 18 years, patients taking monoamine oxidase inhibitors or tricyclic antidepressants, patients with mesenteric or peripheral vascular thrombosis, patients with renal impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac output 5 min after spinal injection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Haemodynamic control - intraoperatively;Umbilical cord blood gases – after delivery;Umbilical cord blood catecholamine concentrations – after delivery; | — |
Countries
China
Contacts
Public ContactProfessor Warwick D. Ngan Kee
Outcome results
None listed