Ischemic stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The first attack of cerebral infarction patients in line with the ICD-10 acute cerebral infarction diagnostic criteria; 2. The TOAST types are include of large-artery atherosclerosis (embolus / thrombosis) and small-vessel occlusion (lacune); 3. Aged 35 to 75 years; 4. Within 14 days - 3 months after the first onset, there are symptoms of cerebral infarction which was confirmed by neuroimaging procedure to rule out hemorrhagic stroke; 5. Written informed consent by patients or their family numbers; 6. There is more than one risk factor of the cerebrovascular disease which can be intervened.
Exclusion criteria
Exclusion criteria: 1. Massive cerebral infarction or coma; Modified Rankin Scale (mRS) score> 4; Water swallow test score >=4; There are other reasons that can not take medication on time; 2. There is an angioplasty in the past for intracranial arterial stenosis; 3. Pregnant or lactating women; 4. Allergic; 5. The TOAST types are include of cardioembolism stroke, other determined aetiology or stroke of undetermined aetiology; 6. Can not complete follow-up of one year being of concomitant diseases such as severe heart disease, cardiac insufficiency, hepatosis, renal inadequacy, respiratory failure and malignancy. Gastrointestinal disorders that affecting drug absorption seriously. Coagulation disorders or previous with systemic hemorrhagic disease. Previous with cerebral hemorrhage; 7. It is concerned by researchers that are not suitable for clinical trials being of other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of stroke;Myocardial infarction;Vascular death;readmission for acute ischemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Medication compliance;Smoking cessation;Exercise;Alcohol consumption;Body weight;Blood pressure;Serum glucose;Serum lipids;Adverse drug reaction; | — |
Countries
China