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A comparison of anesthetic regimens using etomidate and propofol in patients undergoing first-trimester abortions: double blind, randomised clinical trial of safety and efficacy

A comparison of anesthetic regimens using etomidate and propofol in patients undergoing first-trimester abortions: double blind, randomised clinical trial of safety and efficacy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002115
Enrollment
Unknown
Registered
2012-04-05
Start date
2010-08-02
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

first-trimester surgical abortion

Interventions

group P:2mg/kg propofol alone
group PMF:2mg/kg propofol + 1ug/kg fentanyl + 0.02mg/kg midazolam
group E:0.2mg/kg etomidate alone
group EMF:0.2mg/kg etomidate + 1ug/kg fentanyl+ 0.02mg/kg midazolam

Sponsors

Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. age 18–35 years; 2. body weight 45–65 kg; 3. height 150–170 cm; 4. ASA physical status I-II; 5. at 6 to 8 weeks of gestation as confirmed by an ultrasound examination.

Exclusion criteria

Exclusion criteria: 1. with a history of vaginal deliveries; 2. uterine anomaly or any other severe medical conditions; 3. with any psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
Vital signs including pulse oxygen saturation, mean arterial pressure and heart rate;

Secondary

MeasureTime frame
recovery time;side effect;

Countries

China

Contacts

Public ContactYao Shanglong
yao_shanglong@yahoo.com.cn+86 13307128437

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026