Pulmonary Lobectomy
Conditions
Interventions
norepinephrine group (NEG) and liberal fluid admin:intraoperative continuous norepinephrine infusion
liberal fluid administration group (LFG):several 100 mL bolus of Voluven were infused to adjust low blood pressure over 5 minutes during operation
Sponsors
Cancer Hospital, Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 144 consecutive patients American Society of Anaesthesiologists (ASA) physical status I-II, aged 18-80 yr, scheduled for elective pulmonary lobectomy, were enrolled in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria were as follows: age >80 yr, body mass index>30, insulin-dependent diabetes mellitus, congestive heart failure, significant hepatic (liver enzymes >50% upper limit of normal value) or renal (plasma Cr >50% upper limit of normal value) dysfunction, anticoagulant treatment, chronic opioid use, morphine intolerance, contraindication to epidural catheter insertion, intraoperative bleeding amount > 400 mL, difficulties of lung exclusion, and complete pneumonectomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemodynamics;tissue perfusion;renal function; | — |
Secondary
| Measure | Time frame |
|---|---|
| perioperative cardiovascular, respiratory and renal; | — |
Countries
China
Contacts
Public ContactZhiming Tan
Outcome results
None listed