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Randomized clinical trial of preoperative antibiotic prophylaxis in elective hepatectomy

Randomized clinical trial of preoperative antibiotic prophylaxis in elective hepatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002049
Enrollment
Unknown
Registered
2012-03-27
Start date
2011-11-10
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver disease

Interventions

1:Cefuroxime (3.0g) was given before incision
2:placebo

Sponsors

First affiliated Hospital of Xiamen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients who were aged 18 years or older and were scheduled for elective hepatic resection; 2. To be willing to assign informed consent and abide by treatment scheme as well as follow-up plan.

Exclusion criteria

Exclusion criteria: 1. emergency surgery; 2. liver resection performed by laparoscopy; 3. diabetes mellitus under insulin control; 4. treatment with antibiotics within 1 week before surgery; 5. patients with a planned extrahepatic resection; 6. coagulopathy; 7. severe heart disease; 8. pulmonary hypertension; 9. renal insufficiency (ie, serum creatinine >2 mg/dL or requiring dialysis); 10. delectrolyte imbalance; 11. poor compliance.

Design outcomes

Primary

MeasureTime frame
wound infection;Intra-abdominal infection;urinary tract infection;

Countries

China

Contacts

Public ContactBin Li
Binl1962@yahoo.com.cn+86 0592 2139908

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026