Nonfunctioning pituitary tumors
Conditions
Interventions
VIMA GROUP:8% Sevoflurane Oxygen flow 6 L/min Tidal volume method inhalation induction, remifentanil 1ug/kg, rocuronium 0.6 mg/kg, tracheal intubation at TOF value 0, 2ug/kg Fentany were given iv 3 mi
TIVA GROUP:propofol 2mg/kg, remifentanil 1ug/kg, rocuronium 0.6 mg/kg for induction, tracheal intubation at TOF value 0, 2ug/kg fentany were given i.v. 3 minutes before incision. maitain anesthesia w
Sponsors
Department of Anesthesiology,Tongji Hospital,Tongji Medical College of Huazhong University of Science & Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patient accepted transsphenoidal surgery for non-functional pituitary adenoma; Aged 18-65 years old; no gender limitation; ASA1-2; weight 40-80 kg; operation time of 1-2 hours.
Exclusion criteria
Exclusion criteria: Liver and kidney dysfunction; lactating women; preoperative confusion unable to cooperate; obvious respiratory cardiovascular disease; functional pituitary tumor back to ICU with endotracheal tube posoperatively;participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time interval between Narcotend value 80 and extub; | — |
Secondary
| Measure | Time frame |
|---|---|
| anesthesisa recovery time;Narcotrend value at drug withdraw;Narcotrend value at extubation;Time interval between Narcotend value 80 and drug;Postoperative sedation (It was assessed by Ramsay Sedation Score(RSS));Emergence agitation (Emergence agitation was assessed by Restlessness score (RS)); | — |
Countries
China
Contacts
Public ContactFang Luo
Outcome results
None listed