Hemorrhagic Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient with spontaneous basal ganglia hemorrhage (diagnosis according to the Guidelines for the Management of Spontaneous Intracerebral Hemorrhage(2010)); 2. Cranial CT scans revealed: hematoma volume >=30ml (intraventricular hematoma was not included); 3. Patients were admitted in 48 hours since onsets; 4. The age was between 15 to 75 years old; 5. Glasgow Coma Scale 5-12; 6. Systolic pressure >160mmHg at onset; 7. Patient has a history of hypertension; 8. Informed consent signed by patients or their relatives.
Exclusion criteria
Exclusion criteria: 1. Hemorrhage resulted from intracranial aneurysm, vascular malformaions or tumor; 2. histroy of head trauma; 3. Multiple intracerebral hemorrhage; 4. History of mental disorder or neurological disorder; 5. History of coagulation disorder or anticoagulants; 6. Comorbidities including hepatic or renal dysfunction; 7. Poor compliance; 8. Pregnancy; 9. Massive hemorrhage in lateral ventricle (CT revealed that area of hemorrhage was more than 1/2 of cross sectional area of lateral ventrical), or hemorrhage in third or fourth ventrile, combined with ventricular dilation. 10. Brain herniation in terminal stage (bilateral mydriasis, respiratory and circulatory failure).
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| National Institutes of Health Stroke Scale (NIHSS);Barthel Index (BI);Mortality; | — |
Primary
| Measure | Time frame |
|---|---|
| Glasgow Outcome Scale (GOS);Modified Rankin Scale (mRS); | — |
Countries
China