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Comparison of intraoperative penile erection during general anesthesia with propofol, sevoflurane and isoflurane for endourology

Comparison of intraoperative penile erection during general anesthesia with propofol, sevoflurane and isoflurane for endourology: An exploratory randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12002022
Enrollment
Unknown
Registered
2012-03-12
Start date
2012-03-09
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative penile erection during endourology

Interventions

propofol:Anesthesia was induced with penehyclidine (0.01mg/kg), i.v. midazolam(0.03mg/kg), i.v. fentanyl (3ug/kg), i.v. propofol 4ug/ml TCI and i.v. vecuronium (0.1mg/kg) and maintained with propofol
sevoflurane:Anesthesia was induced with penehyclidine (0.01mg/kg), i.v. midazolam(0.03mg/kg), i.v. fentanyl (3ug/kg), inhaling 6% sevoflurane and i.v. vecuronium (0.1mg/kg) and maintained with inhalin
isoflurane:Anesthesia was induced with penehyclidine (0.01mg/kg) , i.v. midazolam(0.03mg/kg) , i.v. fentanyl (3ug/kg) , inhaling 4% isoflurane and i.v. vecuronium (0.1mg/kg) and maintained with inhali

Sponsors

Department of Anesthesiology, West China Hospital, Sichuan University, Chendu
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The male patients (American Society of Anesthesiologists physical status class I or II; age, 18-60 yr) undergoing elective endourology procedure at the urology department of West China Hospital, Sichuan University.

Exclusion criteria

Exclusion criteria: Known or predicted difficult airway, BMI >=30, coronary atherosclerosis disease, chronic renal insufficiency, chronic hepatic insufficiency, erection dysfunction, acute exacerbation of asthma, anterior urethral stricture, or known allergy to medicine during anesthesia.

Design outcomes

Primary

MeasureTime frame
The incidence of intraoperative penile erection of each group;The efficiency of isoflurane for the treatment of intraoperative penile erection;hypotension;heart rate < 50/min;cough;laryngospasm;bronchospasm;movement;arrhythmia;others;The quality of induction;

Secondary

MeasureTime frame
The score of penile erection;non-invasive arterial pressure (NIAP);heart rate;pulse oximetry;Bispectral Index;end-tidal anesthetic-agent (ETAC)concentration;The effect-site concentration of propofol;The fluid volume given during observation;hypertension;

Countries

China

Contacts

Public ContactXinchuan Wei
weixinchuan@163.com+86 18980601553

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026