A prospective randomized controlled clinical trial on sodium valproate in the prophylactic treatment of perioperative epilepsy of elective neurosurgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12001977

Enrollment

Unknown

Registered

2012-02-13

Start date

2012-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy

Interventions

Treatment:sodium valproate 15mg/kg/day

Control:saline

Eligibility

Sex/Gender

All

Age

4 Years to 20 Years

Inclusion criteria

Inclusion criteria: 1. Patients of 4 years old or above; 2. patients with primary supratentorial glioma or metastatic brain tumor.

Exclusion criteria

Exclusion criteria: 1. Patients previously diagnosed as idiopathic epilepsy; 2. Patients have epileptic seizure before surgery; 3. Patients undergo urgent surgery (due to cerebral hernia, tumor Apoplexy); 4. Patients with multiple intracranial tumors or recurrent tumors; 5. Patients have already undergone garma-knife or radiotherapy; 6. Patients with other severe systemic diseases.

Design outcomes

Primary

Measure	Time frame
epileptic attack;	—

Countries

China

Contacts

Public ContactLiangfu Zhou

lfzhouc@online.sh.cn+86 21 52889999

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026