Skip to content

Phase III clinical trial of Astragaloside IV glucose on stable angina of coronary artery disease

Phase III clinical trial of Astragaloside IV glucose on stable angina of coronary artery disease

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12001974
Enrollment
Unknown
Registered
2012-03-01
Start date
2006-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stable angina of coronary artery disease

Interventions

Treatment group:Astragaloside IV glucose injection for 2 weeks
Control group:Salvia miltiorrhize Injection for 2 weeks

Sponsors

Teaching Hospital of Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Patients who fit the diagnostic criteria for angina of coronaryheart disease; (2) Patients who fit the diagnostic criteria for stable effort anginaof coronary heart disease; (3) Effort angina level I, II III; (4) Attack frequency at >2 per week; (5) Electrocardiogram (ECG): S-T segment shift is less than or equalto 0.1 mv and/or along with an inverted T wave in the prominent Rwave lead by a depth of more than 0.2 mv; or electrocardiogram: S-Tsegment shift is less than or equal to 0.05 mv, or less than 0.1 mvwith a positive treadmill exercise test; (6) Age: male: 40-70 years, female: 45-70 years; (7) patients who signed the consent forms.

Exclusion criteria

Exclusion criteria: (1) Acute myocardial infarction, menopaul syndrome, hyperthyroidism, cervical spondylosis, billiard disease, chest pain caused by stomach or esophagus reflux; (2) Hypertensive patients with blood pressure greater than or equal to 160/100 after antihypertensive drug treatment, severe cardiopulmonary dysfunction, severe arrhythmia (atrial fibrillation, atrial flutter, paroxysmal ventricular tachycardia), primary liver, kidney or hematopoietic disease, mental illness; (3) Six months within coronary artery bypass or other surgical intervention; (4) Diabetes; (5) Allergies known allergy to Astragalus; (6) Alcohol allergy; (7) Use of drugs known to have severe impact on liver kidney function within one month; (8) Patients involved in other clinical trials within one month.

Design outcomes

Primary

MeasureTime frame
Number of angina attack;Angina duration;Angina pain;Nitroglycerin consumption;

Countries

China

Contacts

Public ContactHong Ding
dinghongcdu@gmail.com+86 13568843763

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026