Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia in Patients Undergoing Thoracotomy During Anesthesia Recovery Period

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-12001934

Enrollment

Unknown

Registered

2012-02-11

Start date

2012-02-27

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Restlessness

Interventions

Group-Dexmedetomidine:Patients in this group received dexmedetomidine 0.

Group-Saline placebo:Patients in this group received placebo

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists Physical Status (ASA-PS) I or II; 2. undergoing selective thoracotomy;- weight between 45 and 75kg; 3. operation time 2-4 hours.

Exclusion criteria

Exclusion criteria: 1. history of neurologic disease; 2. history of chronic analgesics intake; 3. history of allergic reactions to the experimental durgs; 4. history of renal insufficiency; 5. history of hepatic dysfunction; 6. history of coagulation disorders; 7. women in lactation; 8. participating in other studies.

Design outcomes

Primary

Measure	Time frame
Emergence agitation;	—

Secondary

Measure	Time frame
Postoperative pain at rest;Dosage of analgesics;Breathing recovery time;Extubation time;Recovery time;Postoperative sedation;SBP/DBP;Differences between extubation and Intervention in TNF-alpha, IL-2,IL-6, IL-10, IFN-garma;	—

Countries

China

Contacts

Public ContactFang Luo

luofang0909@hotmail.com+86 18627847412

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026