gout
Conditions
Interventions
TCM-treated ?group:"Yellow-dragon Wonderful-Seed" formula (+Gypsum)
TCM-treated ? group:"Yellow-dragon Wonderful-Seed" formula (-Gypsum)
allopurinol-treated group:allopurinol
Sponsors
Teaching Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Physician diagnosis of gout; 2. Have hyperuricemia (serum urate > 7.0 mg/dl); 3. To be aged 18 years to 70 years; 4. Subjects receiving urate-lowering therapy will undergo a 2-week washout period. Only those whose sUA remain > 7.0 mg/dl after washout period will be included; 5. Sign the informed consent forms.
Exclusion criteria
Exclusion criteria: 1. Age 70 years; 2. Pregnancy or lactation; 3. Severe cardiovascular, brain, liver, kidney and hematopoietic system comorbidities; mental disorders; cancer; 4. Disabled subjects due to severe deforming gouty arthropathy; 5. Concurrent therapy with urate-lowering agents, azathioprine, 6-mercaptopurine, or medications containing aspirin (>325mg) or other salicylates; 6. Serum creatinine >1.5mg/dL or ALT more than doubles the upper limit of the normal range; 7. Arrythmia of clinical significance; 8. Allergic to allopurinol or Traditional Chinese Medicine used in the present study or allergic constitution; 9. A history of alcohol abuse; 10. Subjects participating other clinical trials within the past three months.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| scores on SF-36 scale;uric acid in urine;erythrocyte sedimentation rate (ESR);X ray;C-reactive protein; | — |
Primary
| Measure | Time frame |
|---|---|
| serum urat; | — |
Countries
China
Contacts
Public ContactSen Zhong
Outcome results
None listed