The effect of metformin and glycosidase inhibitors on islet beta and alpha cells function in obese or overweight subjects with type 2 diabetes

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001808

Enrollment

Unknown

Registered

2011-12-06

Start date

2010-02-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

type 2 diabetes

Interventions

2:metformin

1:glycosidase inhibitors

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. new diagnosed type 2 diabetes; 2. BMI 24kg/m2 to 30kg/m2; 3. HbA1c 6.3% to 10%; FBG<=11.1 mmol/L; 4. Voluntary.

Exclusion criteria

Exclusion criteria: 1. Pregnant women, ready to pregnancy or lactating women; 2. dysfunction of liver, ALT>100U/L; 3. serum Cre>133umol/L; 4. severe Gastrointcstinal Disease; 5. severe CHD; 6. SBP>180 mmHg OR DBP>120 mmHg.

Design outcomes

Primary

Measure	Time frame
insulin;glucagon;HbA1c;IL-1;TNF-alpha;	—

Countries

China

Contacts

Public ContactWeiping Sun

sunwp07@163.com+86 13087228833

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026