Combination of probiotics and early enteral nutrition on sepsis and immunity in critically ill trauma patients

combination of probiotics and early enteral nutrition on sepsis and immunity in critically ill trauma patients

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-11001769

Enrollment

Unknown

Registered

2011-09-26

Start date

2011-11-21

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

critically ill trauma patients

Interventions

A:Early enteral nutrition for 21ds

B:Early entaral nutrition for 21ds plus Golden Bifid of 7ds

C:Early entaral nutrition for 21ds plus Golden Bifid of 14ds

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The informed consent is signed, patients and their families have a good compliance; 2. Inpatients with ages between 18-65 and no sex limitation; 3. Be recived among 24h and be certified as critically ill trauma; 4. Have GCS scores between 5-10 or ISS scores greater than 16, the expected survival time greater than 7d; 5. With no severe heart, liver, kidney failure and other diseases.

Exclusion criteria

Exclusion criteria: 1. With severe gastrointestinal, endocrine disorders, gastrointestinal injury; 2. Severely immunocompromised, primary hypoalbuminemia; 3. Severely digestive tract bleeding; 4. Pregnant or lactating women, chemotherapy, cancer patients; 5. Beyond the enteral nutrition by other cause.

Design outcomes

Primary

Measure	Time frame
ICU hospitalization days;Mortality rate;	—

Secondary

Measure	Time frame
Infection rate;	—

Contacts

Public ContactZhu Jingci

zhujingci@163.com+86 023 68771156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026